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Dr. Vinayak Venkatesh shares that Psoriasis is a chronic immune-mediated inflammatory disease that extends beyond the skin, often impacting patients physically, emotionally, and socially. Recent advancements in our understanding of its underlying immunopathogenesis, particularly the role of key cytokine pathways, have transformed treatment strategies. The emergence of targeted biologics and novel systemic therapies has enabled more effective disease control, improved safety profiles, and enhanced quality of life. As clinicians, it is important to integrate these evolving insights into practice to deliver personalized and evidence-based care for patients with psoriasis