Advances in Alopecia Areata Treatment: Focus on JAK inhibitors

The expert discussed emerging therapies for alopecia areata, specifically mentioning Janus kinase (JAK) inhibitors. These are recent medications approved for treatment and can be used both topically and orally. Oral ruxolitinib, typically administered as 5 mg morning and night for 2 to 3 months, is commonly used to limit the spread of the disease. Once the spread is limited, topical tofacitinib, used twice daily, can help promote hair growth. Before starting oral JAK inhibitors, certain investigations are necessary, including ruling out tuberculosis (e.g., Gold TB test), a complete hemogram, liver function test, renal function test, and lipid profile.

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